Majid Takht-Ravanchi, Iran's deputy foreign minister, tells the BBC's Lyse Doucet that the ball was "in America's court to prove that they want to do a deal".
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Clinician Dr Hilary Cass says "people at the extremes" had caused a lot of distress for young people.
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The prime minister's speech comes after a tumultuous week in his political career back home.
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Opposition politicians flocked to a summit in Munich to offer an alternative to America First - and stake a claim as future party leaders.
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The former US president didn't name Trump, but lamented the lack of "shame" and "decorum" among public officials.
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